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Statistics Foundation · Lesson 4.5

Sample size and study design.

Sample size planning connects mathematics with responsible study design. This lesson explains how sample size, variability, effect size, power, allocation, precision, dropout and bias shape the quality of statistical evidence.

155 minutes
No coding
Power planning
Study design

Lesson route

Move from inference interpretation to study planning.

Previous lessons interpreted confidence intervals, p-values and power. This lesson moves earlier in the research process: how should a study be designed so that the evidence is precise, powerful and credible?

0–15 min

Why sample size matters

Understand sample size as a design decision that controls precision, uncertainty and ability to detect meaningful effects.

15–40 min

Precision planning

Learn how margin of error, variability and confidence level determine the sample size needed for a desired interval width.

40–70 min

Power planning

Study how sample size affects the probability of detecting a meaningful effect when that effect truly exists.

70–100 min

Effect size and variability

Explore how smaller effects and higher variability require larger samples.

100–125 min

Allocation and design

Understand how balanced and unbalanced group sizes affect precision in comparative studies.

125–155 min

Quality of evidence

Connect sample size to study design, bias, representativeness, feasibility, ethics and reporting.

Mastery checklist

Students should connect sample size to evidence quality.

1

Calculate sample size for a desired margin of error.

2

Explain why n grows with variability.

3

Explain why smaller effects require larger samples.

4

Adjust sample size for dropout.

5

Compare balanced and unbalanced allocation.

6

Explain diminishing returns from increasing n.

7

Distinguish random error from systematic bias.

8

Report sample size assumptions transparently.