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Statistics Foundation · Lesson 5.4

Multiple regression and confounding.

Multiple regression extends simple regression to several predictors. This lesson explains adjusted coefficients, confounding, crude versus adjusted associations, overadjustment, collider bias, multicollinearity and responsible model choice.

170 minutes
No coding
Adjustment
Confounding

Lesson route

Move from one predictor to adjusted comparisons.

0–20 min

Why simple regression may mislead

Understand why a single predictor relationship may be distorted by other variables.

20–50 min

Multiple regression equation

Learn the model with more than one explanatory variable and interpret adjusted coefficients.

50–80 min

Confounding

Study how a third variable can create or distort an association between exposure and outcome.

80–110 min

Adjustment

Understand what it means to compare observations at the same value of a covariate.

110–140 min

Model choice

Explore why variables should be chosen using research design and subject knowledge, not only automatic statistics.

140–170 min

Interpretation limits

Recognise overadjustment, collider bias, multicollinearity and causal overclaiming.

Mastery checklist

Students should know what adjustment means.

1

Write the multiple regression model.

2

Interpret adjusted coefficients.

3

Explain confounding.

4

Compare crude and adjusted coefficients.

5

Explain overadjustment.

6

Recognise collider bias.

7

Understand multicollinearity.

8

Distinguish prediction from causal explanation.